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Materials and Methods Materials Cyanocobalamin (5, 6-Dimethylbenzimidazolyl cyanocobamide), Thiamine (3-[(4-Amino2methyl5pyrimidinyl) methyl]-5-(2hydroxyethyl)-4methylthiazolium chloride) and pyridoxine (5-Hydroxy6methyl3,4pyridinedimethanol) were obtained from Sigma-Aldrich, Germany (Figure 1)

Relationship between RS, Aging, and Related Diseases Reactive oxygen, nitrogen, and halogen species, collectively referred to as reactive species (RS), are produced through various internal and external processes

Cells 11 , 3112 (2022)