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"Our analyses show that there is significant toxicity in harm reduction products, and reduction of carcinogens in harm reduction mainstream smoke does not necessarily reduce the toxicity of unfiltered sidestream smoke." Researchers developed tests with human embryonic stem cells, which are similar to young embryos, to compare the toxicity of mainstream (inhaled) smoke and sidestream smoke from both conventional and harm reduction cigarette brands

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This month, the United States Food and Drug Administration will publish final regulations on the matter, according to the agencys Spring Regulatory Agenda

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