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The redox signal transduction cascade is a highly complex and coordinated system involving the generation of reactive oxygen species, the oxidation of redox-relay molecules or direct oxidation of sensor molecules with thiol switches like Kelch-like ECH-associated protein 1 (Keap1), and effector molecules that change activity, localization, protein-protein interactions, or protein turnover in response to the redox signaling cascade [6, 7]

Merabet N, Bellien J, Glevarec E, Nicol L, Lucas D, Remy-Jouet I, Bounoure F, Dreano Y, Wecker D, Thuillez C, Mulder P (2012) Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure

Figure 3 Table 1 Other inhibitors of cGAS-STING signaling pathway and their effects

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Your age at diagnosis, the cause and severity of your dementia, and your personal lifestyle choices all contribute to how long you will live with dementia